ngµç×ÓÓÎÏ·ÐÂÎÅÍø£¨Í¨Ñ¶Ô±¿µ¾þÃù£©¿ËÈÕ£¬£¬£¬Á¥ÊôµÚÒ»Ò½ÔºÕûÐÎÍâ¿ÆÌƱùÌÆÇì½ÌÊÚÍŶӷ¢Ã÷£¬£¬£¬ÔÚÌÇÄò²¡´´ÃæÖУ¬£¬£¬Ñª¹ÜÖÜϸ°ûÖм×Áò°±ËáÏÙÜÕתÒÆøMAT2A±í´ïϵ÷£¬£¬£¬²¢ÓëÑ×ÐÔ¾ÞÊÉϸ°û½þÈó³Ì¶È³Ê¸ºÏà¹Ø¡£Ïà¹ØÑо¿½ÒÏþÔÚ¹ú¼Ê×ÅÃûÆÚ¿¯¡¶×ÔÈ»¡¤Í¨Ñ¶¡·¡£´´É˺ó¾ÞÊÉϸ°ûµÄʵʱ½þÈóÓëÓÐÓÃɨ³ý¶Ô´´ÃæÔÙÉúÖÁ¹ØÖ÷Òª¡£È»¶øÔÚÌÇÄò²¡´´ÃæµÈ²¡Àí״̬Ï£¬£¬£¬Ï¸°û¼äÐͬÊÜËðÔõÑùµ¼Ö³ÖÐøµÄÑ×ÐÔ¾ÞÊÉϸ°û½þÈóÈÔ²»ÇåÎú¡£Ñо¿Ê¹ÓÃCspg4-CreERT2/+; Mat2aflox/floxСÊóÄ£×Ó¼°Æä´´Ãæ×éÖ¯µÄµ¥Ï¸°û²âÐòЧ¹ûÅú×¢£¬£¬£¬ÖÜϸ°ûMat2aȱʧ¿É´¥·¢Ï¸°ûÐàÂõ£¬£¬£¬²¢Í¨¹ýÐàÂõÏà¹ØÉø͸±íÐÍSASPÒò×ÓºÍϸ°û¼äÏßÁ£ÌåתÒÆ£¬£¬£¬Çý¶¯¶Ô½þÈó¾ÞÊÉϸ°ûµÄÑ×ÐÔÃâÒßѵÁ·¡£
ÔÚ»úÖÆÉÏ£¬£¬£¬ÖÜϸ°ûÖÐMAT2Aϵ÷Ï÷ÈõÁËÈ¥·ºËØ»¯Ã¸OTUB1ÏòHMGCS1µÄÕÙļ£¬£¬£¬´Ó¶ø½µµÍHMGCS1µÄÂÑ°×±í´ïˮƽ£¬£¬£¬×ÌÈŸ¨Ã¸QºÏ³É£¬£¬£¬Ëðº¦ÏßÁ£Ì幦Ч²¢ÓÕµ¼Ï¸°ûÐàÂõ¡£Ëæºó£¬£¬£¬¹¹½¨°üÔØ×ÔÀ©ÔöRNA£¨self-amplifying RNA, saRNA£©µÄÄÉÃ׿ÅÁ££¬£¬£¬²¢ÒÔÖÜϸ°û·ÂÉúϸ°ûĤ¶ÔÆä¾ÙÐаü±»£¬£¬£¬ÒÔÔÚÐàÂõÖÜϸ°ûÖлָ´Îȹ̵ÄMAT2A±í´ï£¬£¬£¬ÓÐÓûº½â³ÖÐøÐÔÑ×ÐÔ¾ÞÊÉϸ°û½þÈ󣬣¬£¬Ôö½ø´´ÃæÔÙÉú¡£
ÉÏÊöЧ¹ûÌáÐÑ£¬£¬£¬MAT2AÊÇÂýÐÔÑ×ÐÔ´´ÃæµÄDZÔÚÖÎÁưе㣬£¬£¬²¢Îª»ùÓÚ·ÂÉúÕ½ÂԵİÐÏòÐàÂõÖÎÁÆÌṩÁËеÄ˼Ð÷¡£Á¥ÊôµÚÒ»Ò½ÔºÌƱù½ÌÊÚΪ×îºóͨѶ×÷Õߣ¬£¬£¬Á¥ÊôµÚÒ»Ò½ÔºÌÆÇì½ÌÊÚºÍngµç×ÓÓÎÏ·Ö×Áö·ÀÖÎÖÐÐĵËÎñ¹ú½ÌÊÚΪÅäºÏͨѶ×÷Õߣ¬£¬£¬ÁÙ´²²©Ê¿ºóÂÀ¶«Ã÷¡¢¡¢²©Ê¿Ñо¿ÉúÈÎÀס¢¡¢ÕÔ×ÏÈ𡢡¢ÈÙÑ೬ΪÅäºÏµÚÒ»×÷Õß¡£
ÂÛÎÄÁ´½Ó£º£ºhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12658056/
µØµã:¹ãÖÝÊÐиÛÎ÷·135ºÅ Óʱà:510275
µç»°: 020-84112828
ngµç×ÓÓÎÏ·°æȨËùÓÐ COPYRIGHT?1999-2022 , SUN YAT-SEN UNIVERSITY